Ac-Lys-Pro-Arg-7-Amino-4-TriFluoromethylcoumarin, 25 mg

Product Description

Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin

Application Notes

Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin is an fluorescent substrate for Tryptase detection. Tryptases are a group of trypsin-related serine proteases expressed in mast cells and basophils.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Substrate for Assay of Tryptase

Specifications

SKU	03AFC13025
Alternate Names	Ac-Lys-Pro-Arg-AFC; Ac-KPR-AFC
Application Notes	Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin is an fluorescent substrate for Tryptase detection. Tryptases are a group of trypsin-related serine proteases expressed in mast cells and basophils.
Base Catalog Number	AFC13025
CAS #	Not yet assigned
Format	Solid
Molecular Formula	C29H39F3N8O6
Pack Size	25 mg
Protein or Enzyme Type	Activators, Inhibitors & Substrates
Specificity	Other trypsin-like enzymes are cleaved by tripeptide synthetic substrates. The absence of inhibition of Tryptase by classical inhibitors or serine esterase; including soybean trypsin inhibitor; clearly distinguishes tryptase from pancreatic trypsin and from most other serine esterases. Tryptase is inhibited by leupeptin; PMSF; and diisopropyl fluorophosphate.
Unit Definition	One unit is the amount of enzyme that cleaves one micromole of AFC, AMC or MNA per minute, per milliliter at above described conditions.
Usage Statement	Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.