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Ac-Lys-Pro-Arg-7-Amino-4-TriFluoromethylcoumarin, 25 mg
Product Description
Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin
Application Notes
Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin is an fluorescent substrate for Tryptase detection. Tryptases are a group of trypsin-related serine proteases expressed in mast cells and basophils.
Usage Statement
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications
Substrate for Assay of Tryptase
Documents
Datasheet
Datasheet
Specifications
| SKU | 03AFC13025 |
| Alternate Names | Ac-Lys-Pro-Arg-AFC; Ac-KPR-AFC |
| Application Notes | Ac-Lys-Pro-Arg-7-Amino-4-Trifluoromethylcoumarin is an fluorescent substrate for Tryptase detection. Tryptases are a group of trypsin-related serine proteases expressed in mast cells and basophils. |
| Base Catalog Number | AFC13025 |
| CAS # | Not yet assigned |
| Format | Solid |
| Molecular Formula | C29H39F3N8O6 |
| Pack Size | 25 mg |
| Protein or Enzyme Type | Activators, Inhibitors & Substrates |
| Specificity | Other trypsin-like enzymes are cleaved by tripeptide synthetic substrates. The absence of inhibition of Tryptase by classical inhibitors or serine esterase; including soybean trypsin inhibitor; clearly distinguishes tryptase from pancreatic trypsin and from most other serine esterases. Tryptase is inhibited by leupeptin; PMSF; and diisopropyl fluorophosphate. |
| Unit Definition | One unit is the amount of enzyme that cleaves one micromole of AFC, AMC or MNA per minute, per milliliter at above described conditions. |
| Usage Statement | Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Citations