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Application NotesBleomycin Sulfate is an atineoplastic antibiotic.
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
It is used in research as antibiotics; antifungal
|Alternate Names||Blenoxane; Blexane; Bleo|
|Application Notes||Bleomycin Sulfate is an atineoplastic antibiotic.|
|Base Catalog Number||19030610|
|Biochemical Physiological Actions||Bleomycin sulfate binds to DNA, causes ssDNA scission at specific base sequences and inhibits DNA synthesis. This inhibitory action requires bleomycin to bind oxygen and a metal ion. It can also cleave RNA, to a lesser degree but more selectively. It acts as an inducer and regulator of apoptosis and inhibits tumor angiogenesis.|
|Melting Point||71 Â°C|
|Molecular Weight||1512.619 g/mol|
|Pack Size||10 mg|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type, Gloves, respirator|
|Solubility||Soluble (NTP, 1992)|
|Typical Working Concentration||It is recommended for use as a cell culture agent at 10-100 µg/mL.|