Enjoy 30% off select life science products  with free shipping and giveaways with promo code: RESEARCH30 Offer ends October 2, 2020.

Cart
 
Inquire

Flurbiprofen, 25 g

Flurbiprofen, 25 g

$1,068.10
Flurbiprofen

SKU 0215816325

Synonyms
(±)-2-Fluoro-α-methyl-4-biphenylacetic acid; L-790,330
CAS Number
5104-49-4
Molecular Formula
C15H13FO2
Molecular Weight
244.265 g/mol
EC Number
225-827-6
MDL Number
MFCD00079303
Packaging size
25 g
Request a quote
Product Description
Flurbiprofen

Application Notes

Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic, analgesic, and antifungal activity. Oral formulations of flurbiprofen may be used to treat rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen is also used topically during ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to ibuprofen. It is used to study the pathophysiological steps of NSAID enteropathy in the rat and the biotransformation of flurbiprofen by Cunninghamella species.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Anti-inflammatory agent

Specifications
SKU 0215816325
Alternate Names (±)-2-Fluoro-α-methyl-4-biphenylacetic acid; L-790,330
Application Notes Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic, analgesic, and antifungal activity. Oral formulations of flurbiprofen may be used to treat rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen is also used topically during ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to ibuprofen. It is used to study the pathophysiological steps of NSAID enteropathy in the rat and the biotransformation of flurbiprofen by Cunninghamella species.
Base Catalog Number 15816325
Biochemical Physiological Actions Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.
CAS # 5104-49-4
EC Number 225-827-6
Format Powder
Hazard Statements H301
Melting Point 110-111 °C
Molecular Formula C15H13FO2
Molecular Weight 244.265 g/mol
Pack Size 25 g
Personal Protective Equipment Eyeshields, Faceshields, Gloves, respirator cartridges
RTECS Number DU8341000
Safety Symbol GHS06
Solubility Water Solubility8 mg/L (at 22 °C)
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)

Datasheets

Datasheets
English (United States)