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FastPrep Homogenizers and Lysis system
MP Bio offers a complete range of bead beating, cell lysis and tissue homogenization solutions to suit your sample preparation needs.
Utilizing bead-beating technology, the FastPrep system provides complete lysis of virtually any sample type and is suitable in a variety of applications from soil analysis to forensics. Mechanical tissue homogenization with the FastPrep system enables the isolation of DNA, RNA, proteins, and other small molecules while eliminating the need for chemicals or enzymes, which can inhibit downstream processes.
Free Instrument Trial
FastPrep® Instrument Trial
This free trial offer allows you to try a FastPrep® instrument in your lab for sample preparation prior to purchasing.
Choose the right FastPrep homogenizer for your needs
| Image | Description | Sample Capacity | Adapters | Tube Compatability | Cryogenic Lysis | Interface | Pre-Defined Protocols | User Defined Protocols | Min Speed | Max Speed | Acceleration | Deceleration | Motion | Typical Lysis Time (s) | Dimensions | Weight | Loudness | Power requirements | 110/230V switch | Links |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SuperFastPrep-2 |
High-Performance, Handheld Field Lysis system | 2 | No | 2 ml | No | Manual button | No | No | 500 CPM | 4,400 CPM | Ø 500 G | NA | Reciprocating | 5 | 13"L x 3.4"W x 4.6"H | 2.2 kg | < 100 dB | 90-240 V for battery charger, cordless operation | Battery loader spec | |
FastPrep-24 |
Bench-Top Bead Beating Lysis System | Up to 48 | Interchangeable | 2 ml, 4.5 ml, 15 ml, 50 ml | Yes | LCD/membrane keyboard | No | 5 | 4.0 m/s | 6.5 m/s | < 2 sec to max | < 2 sec to stop | Figure 8 tridimentional | 40 | 465 mm (H) x 437 mm (W) x 332 mm (L) | 17.5 kg (45 lb) | 70 dB | 90-250 V AC, 50/60 Hz, 1,200 W | Automatic | |
FastPrep 5G |
Advanced Bench-Top Bead Beating Lysis System | Up to 48 | Interchangeable | 2 ml, 4.5 ml, 15 ml, 50 ml | Yes | Touch Screen | 72 | 12 | 4.0 m/s | 10.0 m/s | < 2 sec to max | < 2 sec to stop | Figure 8 tridimentional | 20 | 490 mm (H) x 472 mm (W) x 385 mm (L) | 23.6 kg (52 lb) | < 70 dB | 120 VAC/60 Hz, 500W; 230 VAC/50 Hz, 500 W |
Automatic | |
FastPrep 96 |
High Throughput, High-Performance Bead Beating Lysis System | Up to 96 | Interchangeable | 2 ml, 4.5 ml, 15 ml, 50 ml, 96 plate, 250 ml | Yes | VFD/ industrial buttons | No | 1 | 800 RPM | 1800 RPM | < 2 sec to max | < 2 sec to stop | Vertical Linear | 40 | 700mm (H) x 440mm (W) x 660mm (L) | 49 kg (108 lb) | < 65 dB | 110 VAC/60 Hz, 5.2A; 220 VAC/50 Hz, 2.6A |
Automatic |
Explore All FastPrep Instruments & Accessories
FastPrep-24™ 5G Instrument
A versatile sample disruption instrument designed to quickly and efficiently homogenize, grind, or lyse biological samples. A completely self-contained system, it eliminates the risk of cross-contamination and time-consuming clean-up associated with manual lysis methods.
FastPrep-24™ Classic Instrument
Grind, homogenize and lyse any sample in 40 seconds or less with the FastPrep-24 Classic. It has been cited in over 8,500 citations, providing researchers consistent results and high yields as a reliable and affordable benchtop instrument.
FastPrep-96™ Instrument
The FastPrep-96 delivers superior performance, speed and reproducibility with high-throughput capabilities – process up to 192 samples simultaneously in 2 x 96 deep well plates. The true linear motion of FastPrep-96 eliminates the need to re-orient plates mid-cycle.
SuperFastPrep-2™
A portable, hand-held sample disruption instrument designed to quickly and efficiently homogenize, grind, or lyse biological and environmental samples. It can be used at remote locations and in most weather conditions for the immediate collection, processing and preservation of samples.
FastPrep Lysing Matrix tubes
The FastPrep Lysing Matrices come in 16 unique matrix compositions to ensure leak and contamination-free homogenization of any sample type without DNA/RNA shearing. FastPrep Lysing Matrices are critical components of the FastPrep sample preparation system.
FastPrep Adapters
MP Bio offers the widest selection of adapters to best meet your sample preparation needs. Adapters allow for sample sizes ranging from 2 mL to 50 mL tubes, 250 mL bottles and 96-deep well plates and are built for durability in ambient and cryogenic conditions.
Frequently Asked Questions
Q: Can I use and leave my FastPrep in a cold room at 4 °C for a long period of time?
A: The operating temperature range for the FastPrep Instruments is from 2 – 48 °C so storing at 4 °C is not a problem. MP Bio has thoroughly tested using and storing a FastPrep in a cold room and have confirmed with other customers. It was built to be used at room temperature so there is a risk of condensation of water and impacting the effect of the motor oil.
Q: Can I use other tubes than the FastPrep Lysing Matrix tubes with my FastPrep Instrument?
A: No. MP Bio has tested a variety of tubes that either did not fit the FastPrep Instrument or were damaged by the vigorous shaking necessary for grinding. The MP Biomedicals Lysing Matrix tubes will provide the best and most accurate results and are the best available for use. BioPulverizer tubes are the only recommended alternative to the FastDNA and FastRNA Tubes.
Q: Should I balance the tubes when using a FastPrep instrument?
A: No. The FastPrep is not a centrifuge and you do need to balance the tubes on adapters.
However, if you do not fill the tube holders completely, avoid having all your tubes in one location. Place your tubes evenly over all the holes in your adapter.
To ensure better stability for the top parts of the adapters, it is important that the adapter rests on more than two points. We recommend using these with a minimum of 4 tubes. Use empty tubes if necessary.
Q: With my new FastPrep 24 I received a set of 8 springs. How do I know when to use them?
A: Each instrument is equipped with two springs. We include these spare springs to prevent delays that could be caused from a spring break. We recommend users change them approximately every two years depending on the frequency and intensity of use of the instrument. The procedure to replace a spring is in the user manual.
Q: There is nothing on the display of the FastPrep-24 Classic or FastPrep-24 5G but it is powered and turned on?
A:The device is shipped with the ‘Emergency Stop’ engaged for safety and will not run until disengaged. Disengage the ‘Emergency Stop’ by turning clockwise until it pops out.
Q: There was a power outage during a run with my FastPrep-24 5G and I need to get my samples back as soon as possible. How do I do that?
A: To open the ‘Dome’, pull the ‘Dome Release Cable’ on back plate of device to release the ‘Dome Latch’.
Q: What is the equivalence of m/s from FastPrep and rpm for other bead beaters?
A: The rpm value refers to the rotation per minutes and the motion on FastPrep-24 is not a rotating motion. The MP Bio FastPrep instrument has a tridimensional motion (8 motion) and m/sec refers to the distance done by the sample or bottom during one second. To convert from rpm to m/s, compare the number of turns carried out by the axis of the engine against the meter per second below.
Motor speed at 4.m/s is between 3400 to 4100 rpm
Motor speed at 6.5 m/s is between 3700 to 4500 rpm
This depends on the adapter used and the distance from tubes to the axis of the FastPrep.
Q: My tubes leaked while using the FastPrep Instrument. Why?
A: If the FastPrep Instrument is run at speeds higher than recommended, it is possible that the heavy ceramic spheres and cylinders can either crack the tubes or weaken the bottoms so that they break when spun. If working with samples that are difficult to lyse, run the FastPrep Instrument at the highest recommended speed for 20-30 seconds, place the tubes in an ice bath to cool, then process the samples again in the FastPrep Instrument. This can be repeated until lysis is complete.
The tubes may also leak if there less than a 0.5 mL empty space inside the tube. During mechanical lysis, the temperature inside the tube rises, increasing the pressure, which can lead to tube failure.
Q: Is it possible to isolate virus particles from animal tissues with the FastPrep System?
A: Yes, using Lysing Matrix A tubes to induce the lysis of viruses together with the animal cells. When the garnet sand is removed and the homogenization process is performed with one ceramic bead, the animal cells are lysed but not the virus, keeping the protein capsid intact. To perform this, set the FastPrep Instrument at a speed of 6.5 m/s for 20 seconds. Reference: Klempa B. et al. (2005) J.Clin.Microbiol. Vol 43(6); 2756-2763.
Q: What setting is recommended for a successful homogenization of skin samples?
A: Use Lysing Matrix A and do 4 runs of 20 seconds on the FastPrep Instrument at a speed of 6.0 m/s. Incubate samples on ice for 2 minutes between each run.
Bead Beating Resources
Sample Preparation Brochure
A comprehensive solution from tissue homogenization through to purification of DNA, RNA and proteins.
Environmental Brochure
From sample preparation to molecular analysis of environmental samples including soil, plant tissue and feces.
Challenges in Plant Research
Discover our range of reagents and instruments designed to meet the challenges of plant research.
Have an old FastPrep Instrument that you’d like to trade in?
Upgrade the performance of your homogenization with the FastPrep-24™, FastPrep-24™ 5G or FastPrep-96™and save by trading-in your old instruments. We accept all types of sample preparation instruments including broken instruments, competitor instruments, and damaged equipment.
MPure-12™ Automated Nucleic Acid Purification System
117002200
Fully automated and integrated platform to purify nucleic acids of the highest yield and purity for downstream applications.
FastPrep-96™ high-throughput bead beating grinder and lysis system
116010500
FastPrep-96™ high-throughput bead beating grinder and lysis system
FastProtein™ Red Matrix
116550600-CF
Kit designed for the rapid extraction of proteins from yeast cells, fungi and algea in a few seconds.
FastProtein™ Blue Matrix
116550400-CF
Kit designed for the rapid extraction of proteins from gram (+/-) bacteria in a few seconds.
AquaPhenol™/Ready-Red™ Kit
11AQUARED1-CF
Kit contains two bottles of Ready-Red and one bottle of AquaPhenol
GENECLEAN® Turbo GNomics Salt Solution
111102206-CF
Aqueous solution of guanidine chaotropic binding salt optimized for the purification of genomic sized DNA.
GENECLEAN® SPIN Glassmilk®
111101201-CF
Prepared aqueous suspension of proprietary silica matrix that contains TBE Modifier so it can be used with TAE- or TBE-buffered agarose gels.
Ready-Red™ mixture
11RYRED001-CF
Ready to use mixture of chloroform and isoamyl alcohol for phebol-based nucleic acid extractions.
FastDNA™ SPIN Kit for Soil Samples, 50 preps
116560200-CF
For the isolation of high-quality bacterial, fungal, plant, and animal genomic DNA from soil and other environmental samples. Uses Lysing Matrix E for cell lysis and a silica-based spin filters for purification.
FastDNA™ SPIN Kit, 100 preps
116540600-CF
Used with any FastPrep® Instrument to lyse and subsequently isolate DNA from up to 200 mg of almost any sample in less than 30 minutes. Updated version of the well-known FastDNA™ Kit.
RapidPure Plasmid Mini Kit
112066200-CF
Designed to isolate up to 20 μg of plasmid DNA from 1.5 mL of an overnight bacterial culture in less than 15 min. All steps can be carried out in either a microcentrifuge or vacuum manifold.
GNOME® DNA Isolation kit
112010400-CF
For quick and efficient isolation of up to 100 µg of high molecular weight genomic DNA from cells and tissues of any type, including bacteria, yeast, plant, and animal cells.
MERmaid® Spin Kit
111105200-CF
For the rapid purification of small MW single-stranded or double-stranded DNA (10 bp to 200 bp) from solutions, agarose gels or polyacrylamide gels
GENECLEAN® Turbo Kit
111102200-CF
Flexible kit designed for the purification of DNA fragments of sizes 0.1 – 300 kb from TAE or TBE buffered agarose gels, PCR reactions and other enzymatic solutions.
GENECLEAN® SPIN Kit
111101200-CF
For the rapid purification of DNA fragments of 0.2 – 20 kb from solutions and agarose gels using spin columns.
Glassmilk® silica matrix
111001204-CF
Aqueous suspension of proprietary silica matrix. Used to bind DNA during purification procedures that utilize the GENECLEAN® Technology.
NEW Wash Buffer, concentrate
111001202-CF
Concentrated solution of NaCl, Tris, and EDTA supplied with the GeneClean® kits.
Sodium Phosphate Buffer
116560205-CF
Component of the FastDNA SPIN Kit for Soil and FastDNA SPIN Kit for Feces.