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Pimaricin, 20 mL
Pimaricin
Application Notes
Pimaricin is an amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis1 and as a fungicide in agar media.
Usage Statement
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Key Applications
Antibiotic
SKU | 0215625420 |
Alternate Names | Antibiotic A-5283; Mycophyt; Natacyn; Pimafucin; Tennecetin; Natamycin preparation |
Application Notes | Pimaricin is an amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis1 and as a fungicide in agar media. |
Base Catalog Number | 15625420 |
Beilstein Registry Number | 1614878 |
Biochemical Physiological Actions | An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane. |
CAS # | 7681-93-8 |
EC Number | 231-683-5 |
Format | Suspension |
Melting Point | 290 dec °C |
Molecular Formula | C33H47NO13 |
Molecular Weight | 665.733 g/mol |
Pack Size | 20 mL |
Personal Protective Equipment | Eyeshields, Gloves |
pH | 5,5-7,5 (1 % w/v solution in previously neutralised mixture of 20 parts <a class="pubchem-internal-link CID-6228" href="https://pubchem.ncbi.nlm.nih.gov/compound/dimethylformamide">dimethylformamide</a> and 80 parts of <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>) |
RTECS Number | TK3325000 |
Solubility | <h5 class="minor-section-title">Water Solubility</h5>4100 mg/L (at 21 °C) |
Usage Statement | Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |