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Sorbitol dehydrogenase, 5 mg

Sorbitol dehydrogenase, 5 mg

$511.70

Key features and details

Sorbitol Dehydrogenase

SKU: 0215664205

Synonyms
L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH
CAS Number:
9028-21-1
MDL Number:
MFCD00131994
Packaging size:
5 mg
Product Description

Sorbitol Dehydrogenase

Application Notes

Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Cabrohydrate metabolism

Documents

Datasheet

Datasheet
Specifications
SKU 0215664205
Alternate Names L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH
Application Notes Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes.
Base Catalog Number 15664205
Biochemical Physiological Actions Activity of sorbitol dehydrogenase increases in diabetic animals.
CAS # 9028-21-1
Format Powder
Hazard Statements H317
Pack Size 5 mg
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Source Sheep Liver
Specific Activity ≥20 u/mg protein
Specificity Reduces L-iditol to L-sorbose. Also acts on D-glucitol and other closely related sugar alcohols. Allows the reduction of ketones to polyols. The reduction of D-fructose is favored. However; alkaline pH shifts the equilibrium in favor of sorbitol oxidation. SDH does not oxidize erythritol; D- or L-arabitol; D-iditol; D-mannitol or inositol. It will not reduce D-tagatose; D-mannoheptulose; D-glucose; DL-glyceraldehyde; pyruvate; 2-oxolutarate or acetaldehyde.
Unit Definition One unit will convert 1.0 umole of D-fructose to D-sorbitol per minute at pH 7.6 at 25 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Citations