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Veratridine, 10 mg

Veratridine, 10 mg

$175.15
Veratridine

SKU: 0215900710

Synonyms
4,9-Epoxycevane-3, 4, 12, 14, 16, 17, 20-Heptol-3-(3, 4-Dimethoxybenzoate); 3-Veratroylveracevine; (3β, 4α,16β)-4,9-epoxycevane- 3, 4, 12, 14, 16, 17, 20-heptol 3-(3,4-dimethoxybenoate)
CAS Number:
71-62-5
Molecular Formula:
C36H51NO11
Molecular Weight:
673.8 g/mol
Beilstein Registry Number:
78875
EC Number:
200-758-4
MDL Number:
MFCD00082515
Packaging size:
10 mg
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Product Description
Veratridine

Application Notes

It has been used as an insecticide, acting as a paralytic agent with higher toxicity to insects than to mammals. It is also used to increase membrane sodium permeability. It has been used to study Na+ channel blockers such as vincamine and vincanol by inducing Na+ channels in the presence and absence of the drugs being tested.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Alkaloid

Specifications
SKU 0215900710
Alternate Names 4,9-Epoxycevane-3, 4, 12, 14, 16, 17, 20-Heptol-3-(3, 4-Dimethoxybenzoate); 3-Veratroylveracevine; (3β, 4α,16β)-4,9-epoxycevane- 3, 4, 12, 14, 16, 17, 20-heptol 3-(3,4-dimethoxybenoate)
Application Notes It has been used as an insecticide, acting as a paralytic agent with higher toxicity to insects than to mammals. It is also used to increase membrane sodium permeability. It has been used to study Na+ channel blockers such as vincamine and vincanol by inducing Na+ channels in the presence and absence of the drugs being tested.
Base Catalog Number 15900710
Beilstein Registry Number 78875
Biochemical Physiological Actions Opens voltage-dependent Na+ channels and prevents their inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue. Veratridine is cytotoxic to chromaffin cells in vitro.
CAS # 71-62-5
EC Number 200-758-4
Format Powder
Hazard Statements H300-H310-H315-H319-H330-H335-H361-H373-H412
Melting Point 180 DEG C
Molecular Formula C36H51NO11
Molecular Weight 673.8 g/mol
Optical Rotation +4.9° (25 mg/mL, ethanol, 25°C(Lit.)
Pack Size 10 mg
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves, respirator cartridges
Purity ≥97%
RTECS Number YX5600000
Safety Symbol GHS06, GHS08
Solubility SOL IN <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/WATER">WATER</a>; SLIGHTLY SOL IN ETHER
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance 262 nm (ethanol)(Lit.)
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)

Datasheets

Datasheets
English (United States)